ATP

C. difficile

Vaccine-mediated stimulation of gut immune system

Oral vaccination with ApyraVax

ApyraVax mechanism

Infection by Clostridioides difficile

Secretory IgA

Normal intestinal homeostasis

Generation of high-affinity secretory IgA

Back to normal intestinal homeostasis

C. difficile clearance by high-affinity secretory IgA

Technology

The ApyraVax technology exploits the delivery of apyrase together with desired antigen/s.The innovative feature is the unique ability to generate high-affinity secretory IgA that are protective towards the target infectious agent.

Technology

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